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Lumba S, Bunsick M, McCourt P. Chemical genetics and strigolactone perception [version 1; referees: 2

approved] F1000Research 2017, 6(F1000 Faculty Rev):975

Lumba S, Subha A, McCourt P. Found in Translation: Applying Lessons from Model Systems to Strigolactone Signaling in Parasitic Plants. Trends Biochem. Sci. 2017 epub ahead of print

Lumba S, Holbrook-Smith D, McCourt P. The perception of strigolactones in vascular plants. Nature. Chem. Biol. 2017 13, 599-606.



Farnesylation mediates brassinosteroid biosynthesis to negatively regulate abscisic acid responses in Arabidopsis. Northey J, Liang S, Jamshed M, Deb S, ,Foo E, Dr. Reid J, Samuels M, McCourt P. Nature Plants, 2016 25:2:16114.


Small molecule antagonists of germination of the parasitic plant Striga hermonthica. Holbrook-Smith D, Toh S, Tsuchiya Y, McCourt P. Nature Chem Biol. 2016 12, 724–729


ERF11 promotes internode elongation by activating gibberellin biosynthesis and signaling pathways in Arabidopsis. Zhou X, Zhang ZL, Yusuke J, Qiu K, Park J, Nam EA, Lumba S, Desveaux D, McCourt P, Kamiya Y, Tyler L, Sun TP 2016 Plant Physiol. 2016 171, 2760-2770.


The small molecule hyperphyllin enhances leaf formation rate and mimics shoot mersitem integrity defects associated with AMP1 deficiency. Poretsha O, Yang S, Pitorre D, Rozhon W, Zwerger K, Uribe MC, May S, McCourt P, Poppenberger B, Sieberer T. Plant Physiol. 2016 171:1277-1290.




50 years of Arabidopsis research: highlights and future directions.Provart NJ, Alonso J, Assmann SM, Bergmann D, Brady SM, Brkljacic J, Browse J, Chapple C, Colot V, Cutler S, Dangl J, Ehrhardt D, Friesner JD, Frommer WB, Grotewold E, Meyerowitz E, Nemhauser J, Nordborg M, Pikaard C, Shanklin J, Somerville C, Stitt M, Torii KU, Waese J, Wagner D, McCourt P. New Phytol. 2015  209:921-44


Structure-function analysis identifies highly sensitive strigolactone receptors in Striga. Toh S, Holbrook-Smith D, Stogios PJ, Onopriyenko O, Lumba S, Tsuchiya Y, Savchenko A, McCourt P. Science 2015 350:203-7

Probing strigolactone receptors in Striga hermonthica with fluorescence. Tsuchiya Y, Yoshimura M, Sato Y, Kuwata K, Toh S, Holbrook-Smith D, Zhang H, McCourt P, Itami K, Kinoshita T, Hagihara S. Science 2015 349:864-8



Towards personalized agriculture: what chemical genomics can bring to plant biotechnology. Stokes ME, McCourt P. Front Plant Sci 2014 5:344


Detection of Parasitic Plant Suicide Germination Compounds Using a High-Throughput Arabidopsis HTL/KAI2 Strigolactone Perception System. Toh S, Holbrook-Smith D, Stokes ME, Tsuchiya Y, McCourt P. Chem. Biol. 2014 2:988-98

A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis. Lumba S, Toh S, Handfield LF, Swan M, Liu R, Youn JY, Cutler SR, Subramaniam R, Provart N, Moses A, Desveaux D, McCourt P. Dev. Cell 2014 29:360-72



ABI3 controls embryo degreening through Mendel's I locus. Delmas F, Sankaranarayanan S, Deb S, Widdup E, Bournonville C, Bollier N, Northey JG, Samuel MA. McCourt P. Proc. Natl. Acad. Sci. 2013 110:E3888-94

Characterization of a cruciferin deficient mutant of Arabidopsis and its utility for overexpression of foreign proteins in plants. Lin Y, Pajak A, Marsolais F, McCourt P, Riggs CD. PLoS ONE 2013 8:e64980

Forward genetic screening for the improved production of fermentable sugars from plant biomass. Stamatiou G, Vidaurre DP, Shim I, Tang X, Moeder W, Bonetta D, McCourt P. PLoS ONE 2013 8:e55616



HY5 is involved in strigolactone-dependent seed germination in Arabidopsis. Toh S, McCourt P, Tsuchiya Y. Plant Signal Behav 2012 7:556-8

The embryonic leaf identity gene FUSCA3 regulates vegetative phase transitions by negatively modulating ethylene-regulated gene expression in Arabidopsis. Lumba S, Tsuchiya Y, Delmas F, Hezky J, Provart NJ, Shi Lu Q, McCourt P, Gazzarrini S. BMC Biol. 2012;10:8

Thermoinhibition uncovers a role for strigolactones in Arabidopsis seed germination. Toh S, Kamiya Y, Kawakami N, Nambara E, McCourt P, Tsuchiya Y. Plant Cell Physiol. 2012 53:107-17

Strigolactones as small molecule communicators. Tsuchiya Y, McCourt P. Mol Biosyst 2012 8:464-9



Next-generation mapping of Arabidopsis genes. Austin RS, Vidaurre D, Stamatiou G, Breit R, Provart NJ, Bonetta D, Zhang J, Fung P, Gong Y, Wang PW, McCourt P, Guttman DS. Plant J. 2011 67:715-25



A small-molecule screen identifies new functions for the plant hormone strigolactone. Tsuchiya Y, Vidaurre D, Toh S, Hanada A, Nambara E, Kamiya Y, Yamaguchi S, McCourt P. Nat. Chem. Biol. 2010 O6:741-9

Plant nuclear hormone receptors: a role for small molecules in protein-protein interactions. Lumba S, Cutler S, McCourt P. Annu. Rev. Cell Dev. Biol. 2010 26:445-69

Arabidopsis: a rich harvest 10 years after completion of the genome sequence. McCourt P, Benning C. Plant J. 2010 61:905-8

Plant chemical genetics. McCourt P, Desveaux D. New Phytol. 2010 185:15-26



Strigolactones: a new hormone with a past. Tsuchiya Y, McCourt P.Curr. Opin. Plant Biol. 2009 12:556-61

Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins. Park SY, Fung P, Nishimura N, Jensen DR, Fujii H, Zhao Y, Lumba S, Santiago J, Rodrigues A, Chow TF, Alfred SE, Bonetta D, Finkelstein R, Provart NJ, Desveaux D, Rodriguez PL, McCourt P, Zhu JK, Schroeder JI, Volkman BF, Cutler SR. Science 2009 324:1068-71

CHOTTO1, a double AP2 domain protein of Arabidopsis thaliana, regulates germination and seedling growth under excess supply of glucose and nitrate. Yamagishi K, Tatematsu K, Yano R, Preston J, Kitamura S, Takahashi H, McCourt P, Kamiya Y, Nambara E. Plant Cell Physiol. 2009 50:330-40

Using reverse genetics to develop small knockout collections for specific biological questions. Northey J, McCourt P. Methods Mol. Biol. 2009 495:1-10



The ABA receptors -- we report you decide. McCourt P, Creelman R. Curr. Opin. Plant Biol. 2008 11:474-8

A novel role for protein farnesylation in plant innate immunity. Goritschnig S, Weihmann T, Zhang Y, Fobert P, McCourt P, Li X. Plant Physiol. 2008 148:348-57

The synthesis of the rhamnogalacturonan II component 3-deoxy-D-manno-2-octulosonic acid (Kdo) is required for pollen tube growth and elongation. Delmas F, Séveno M, Northey JG, Hernould M, Lerouge P, McCourt P, Chevalier C. J. Exp. Bot. 2008 59:2639-47



High-throughput screening of small molecules for bioactivity and target identification in Caenorhabditis elegans. Burns AR, Kwok TC, Howard A, Houston E, Johanson K, Chan A, Cutler SR, McCourt P, Roy PJ. Nat Protoc 2006 4:1906-14

Plant hormone receptors: perception is everything. Chow B, McCourt P. Genes & Dev. 2006 20:1998-2008

A small-molecule screen in C. elegans yields a new calcium channel antagonist. Kwok TC, Ricker N, Fraser R, Chan AW, Burns A, Stanley EF, McCourt P, Cutler SR, Roy PJ. Nature 2006 441:91-5



Plant biology: a receptor for gibberellin. Bonetta D, McCourt P. Nature 2005 437:627-8

Preventing leaf identity theft with hormones. Lumba S, McCourt P. Curr. Opin. Plant Biol. 2005 8:501-5

Molecular tailoring of farnesylation for plant drought tolerance and yield protection. Wang Y, Ying J, Kuzma M, Chalifoux M, Sample A, McArthur C, Uchacz T, Sarvas C, Wan J, Dennis DT, McCourt P, Huang Y. Plant J. 2005 43:413-24

Dude, where's my phenotype? Dealing with redundancy in signaling networks. Cutler S, McCourt P. Plant Physiol. 2005 38:558-9



The transcription factor FUSCA3 controls developmental timing in Arabidopsis through the hormones gibberellin and abscisic acid. Gazzarrini S, Tsuchiya Y, Lumba S, Okamoto M, McCourt P. Dev. Cell 2004 7:373-85

Systems approaches to understanding cell signaling and gene regulation. Provart NJ, McCourt P. Curr. Opin. Plant Biol. 2004 7:605-9

The FUS3 transcription factor functions through the epidermal regulator TTG1 during embryogenesis in Arabidopsis. Tsuchiya Y, Nambara E, Naito S, McCourt P. Plant J. 2004 37:73-81

Hormone signalling from a developmental context. Chow B, McCourt P. J. Exp. Bot. 2004 55:247-51



Cross-talk in plant hormone signalling: what Arabidopsis mutants are telling us. Gazzarrini S, McCourt P. Ann. Bot. 2003 9:605-12

The ABSCISIC ACID INSENSITIVE 3 (ABI3) gene is modulated by farnesylation and is involved in auxin signaling and lateral root development in Arabidopsis. Brady SM, Sarkar SF, Bonetta D, McCourt P. Plant J. 2003 34:67-75

Hormone evolution: The key to signalling. Kushiro T, Nambara E, McCourt P. Nature 2003 422:122



A screen for genes that function in abscisic acid signaling in Arabidopsis thaliana. Nambara E, Suzuki M, Abrams S, McCarty DR, Kamiya Y, McCourt P. Genetics 2002 161:1247-55



Genetic analysis of hormone signaling. McCourt P .Annu. Rev. Plant Physiol. Plant Mol. Biol. 1999 50:219-243


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